Human Sera
Cayman Chemical Ketotifen (fumarate), Purity: ≥98%, CAS: 34580-14-8, 100 mg
A histamine H1 receptor antagonist (Ki = 1.3 nM) and mast cell stabilizer; selective for H1 receptors over H2 and H3 receptors (Kis = 987 and 2,500 nM, respectively); inhibits compound 48/80-induced degranulation of rat peritoneal mast cells at 50 and 100 μM; inhibits the PCA reaction in rats by 54.6% at 20 mg/kg; inhibits the quick phase airway response in a rat ovalbumin-induced immediate airway response model at 30 mg/kg
Cayman Chemical Domperidone, Purity: ≥98%, CAS: 57808-66-9, 100 mg
A dopamine D2 receptor antagonist (Ki = 0.3 nM in CHO cells expressing the rat receptor); selective for dopamine D2 over D3 receptors (Ki = 9.5 nM); inhibits dipropyl dopamine-induced femoral vasodilation in dogs at 0.5-5 μg/kg; prevents dopamine-induced decreases in pentagastrin-induced gastric antral motility in dogs at 0.5 mg/kg; inhibits apomorphine-induced emesis in dogs (ED50 = 0.031 mg/kg, p.o.); increases serum levels of prolactin in male rats
Sino Biological Recombinant Human C5AR1/C5R1/CD88 Protein (VLP, Full-Length, Flag Tag)
A DNA sequence encoding the Human C5AR1 (P21730) (Met1-Val350) was expressed with a flag tag at the N-terminus.
Cayman Chemical Zerumbone, Purity: ≥95%, CAS: 471-05-6, 50 mg
A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM); inhibits SHH signaling and induces apoptosis in cancer cell lines
Cayman Chemical Teicoplanin Complex, Purity: ≥95%, CAS: 61036-62-2, 100 mg
A mixture of closely related metabolites produced by A. teichomyceticus that are effective against Gram-positive bacteria; prevents bacterial cell-wall synthesis by binding and sequestering a cell-wall precursor with a D-alanine-containing peptide
Cayman Chemical Fenoldopam (mesylate), Purity: ≥95%, CAS: 67227-57-0, 50 mg
An agonist of dopamine D1A (D1R) and D1B (D5R) receptors (Kds = 17 and 11 nM, respectively); alters hemodynamic properties, including hypertension, in animals.
Cayman Chemical Elvitegravir, Purity: ≥98%, CAS: 697761-98-1, 100 mg
A quinolone antibiotic that inhibits HIV-1 integrase (IC50 = 7.2 nM); has antiviral activity against laboratory strains and clinical isolates of HIV-1 in MAGI cells (EC50s = 0.1-1.26 nM) and HIV-2 in PBMCs (EC50s = 0.3-0.9)
Cayman Chemical Temocapril (hydrochloride), Purity: ≥98%, CAS: 110221-44-8, 50 mg
A prodrug form of temocaprilat; prevents impairment of acetylcholine-induced relaxation in aortic rings isolated from diabetic rats in a model of streptozotocin-induced diabetes; inhibits the angiotensin I-induced pressor response in normotensive rats at 0.1, 0.3, and 1 mg/kg; prevents coronary vascular remodeling induced by L-NAME in rats at 0.1 mg/ml in the drinking water; reduces plasma glucose levels in a KKAy mouse model of type 2 diabetes at 1 mg/kg
Cayman Chemical Monobromobimane, Purity: ≥98%, CAS: 71418-44-5, 50 mg
A thiol-reactive fluorogenic probe; used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides
Cayman Chemical Glufosinate (ammonium salt), Purity: ≥95%, CAS: 77182-82-2, 100 mg
A broad-spectrum herbicide; an irreversible inhibitor of GS1 and GS2 (Kis = 1.1. and 4.8 µM, respectively); reduces dry biomass of the weeds E. canadensis and L. rigidum (ED50s = 26 and 763 g/hectare, respectively); has no observed adverse effects in rats and mice at 4.1 and 17 mg/kg per day for three months
Cayman Chemical (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane, Purity: ≥98%, CAS: 257641-01-3, 100 mg
A dithiol used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality
Cayman Chemical Isoxanthopterin, Purity: ≥90%, CAS: 529-69-1, 50 mg
A natural intermediate in the pteridine pathway that can be produced naturally from 7-oxobiopterin or in vitro by the oxidation of pterin by xanthine oxidase
Cayman Chemical Cefamandole (sodium salt), Purity: ≥90%, CAS: 30034-03-8, 100 mg
A cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza and S. aureus
Cayman Chemical Bambuterol (hydrochloride), Purity: ≥95%, CAS: 81732-46-9, 100 mg
A prodrug form of terbutaline; an inhibitor of BChE (IC50 = 3.9 nM for the human enzyme); increases the latency to histamine-induced collapse in guinea pigs at 1 and 2 mg/kg; completely inhibits ovalbumin-induced decreases in dynamic compliance and increases in pulmonary resistance in ovalbumin-sensitized guinea pigs at 10 mg/kg
Cayman Chemical Asiaticoside, Purity: ≥95%, CAS: 16830-15-2, 50 mg
The main saponin constituent of C. asiatica that has been shown to improve wound healing including increasing collagen synthesis and elevating antioxidant levels in various normal and diabetic wound models